Worlds first portable dry laser peel

"Mediderm® is an exciting new laser technology that gives a more significant effect on rejuvenating the epidermis than we see with microdermabrasion. Treatment is painless and without the sequela of ablative laser therapy".

- Dr. Neil Sadick, M.D. clinical professor Cornell University,
New York City

"Those who previously had Microdermabrasion feel that the MediDerm® is more effective in terms of skin smoothing "
– Dr. Neil Sadick, M.D. clinical professor Cornell University, New York City

"I found encouraging results for stretch marks."
- Dr Aurora DeJuliis, Bloomfield, NJ

"...one of my patients called to tell me MediDerm® was the 'best thing she'd ever done for herself,' she said the results were absolutely amazing and she swears it took ten years off."
–Connie Nutter, Moeller Dermatology, Wichita, KS

"Several sessions spaced a few weeks apart will smooth the skin, soften pores and improve discoloration."
- Dr Alan Rosenbach, Los Angeles, CA

"MediDerm® has proven to be a safe reliable and affordable addition to my cosmetic practice."
- Dr Ken Rotskoff, Clayton Medical Spa, St. Louis, MO

"Treatment also helps smooth out the outer layer of the skin. The MediDerm® can also lighten, and sometimes completely remove lentigos. In addition, treatment can help with minor imperfections of the skin and signs of sun damage."
- says Dr. Moeller of the University of Wichita, Kansas

What is the MediDerm® laser?

MediDerm® employs a patented, controlled energy, Erbium YAG solid-state laser (less than 1 joule) that delivers a beam of collimated light energy at a 2940 nanometers wavelength.

Energy at this wavelength is absorbed almost entirely by water. When this beam of energy impinges on the skin, the top layer of skin (often over hydrated with excessive water in the interstitial spaces between the cells) flash evaporates, causing controlled tissue vaporization/cell ablation. The water is thermally driven from the spaces. This allows other cells to expand into the space once occupied by this excess water. Thus revealing rejuvenated and tightened skin. While MediDerm® is not a therapeutic device designed specifically to treat an illness or injury, it yields superior cosmetic and aesthetic results for the skin.

Is the MediDerm® different from other Erbium lasers?

Absolutely. Old style high energy Erbium lasers results take weeks to heal and are too aggressive and painful for most patients. The unique power and pulse length of the MediDerm® laser is very different from old Erbium lasers. Furthermore, MediDerm® utilizes new patented, solid state laser technology which requires no calibration or maintenance unlike the old style Erbiums using articulating arms with mirrors.

How is MediDerm® positioned in relation to other cosmetic procedures?

The MediDerm® is positioned between basic MicroDermabrasion or Intense Pulsed Light and the more extreme and expensive surgical lifts and strong chemical peels. The result is looking and feeling years younger with softer, smoother healthier looking skin.

What are the MediDerm® results?

The ablated layer of the skin will peel completely within 2-7 days. During this time period, the appearance of the exfoliating skin can be minimized or eliminated by use of a moisturizer or make-up. Some skin care professionals might recommend a cleansing face scrub or other exfoliation treatment during this time period.

The MediDerm® can reduce fine lines or wrinkles and give the newly exposed surface layer of skin a more uniform texture and younger look.

Is MediDerm® easy to use?

The MediDerm® is very easy to use and control.

The Patented, ergonomically designed laser hand-piece weighs just a few ounces. The flexible cable delivers both the power and the cooling system to the hand-piece. No mirrors, no expensive fiber optics, no alignment issues, and no long term laser downtime. The compact nature of the system reduces technician fatigue while delivering an effective aesthetic procedure. The MediDerm® has multiple power and speed settings giving you total control.

What should our patients expect
after the MediDerm®?

• A very mild stinging sensation for the first several hours. This can be relieved with a cold compress. Moisturizers or creams should not be used during this time period unless approved by your clinician.

• Some degree of redness. Some areas may appear more red than others which will diminish during the regeneration period as your face peels and can be easily covered with make-up.

• Complete Face peel & recovery in 5-7 days.

What is the MediDerm® regimen?

Similar to Botox®, results are not permanent and most patients will elect a MediDerm® regimen of 3 or 4 visits to maintain the benefits.

MediDerm Laser Model: MED500

Power Settings: Clinically derived optimal fluences.

High - Deepest peel possible without blistering or oozing.

Med - Medium depth peel.

Low - Lowest power while still yielding a very light peel.

Pulse Repetition Rate: 3 Hz, 6 Hz, 9 Hz
(9 Hz full face peel: 30 minutes)

Spot Size: 5mm

Wavelength: 2940nm

Total Energy: Less than 1 Joule

Dimensions : 35.6 cm x 43.2 cm x 20.3 cm
(14”w x 17”d x 8”h)

Console Weight: 13.6 Kg (30 lbs)

Handpiece Weight: 0.45 Kg (1 lbs)

Global Electrical input: 100v to 240v worldwide 50 to 60 cycles (automatically adapts internally)

Made in the USA Patent #5,548,604

Total Control. Easy to Maintain.

• Patented, ergonomic laser hand piece is light and easy to handle
• The compact hand piece reduces technician fatigue
• Multiple power and speed settings allows total control
• Flexible cable delivers the power and the cooling system to the hand piece
• No mirrors, no fiber optics, no alignment issues, and no laser downtime
• Just clean the lens once during and once after the procedure

A Prospective Clinical and Histological Study to Evaluate the Efficacy and Safety a Low Energy Micro-Ablative
Erbium YAG Technology for Facial Rejuvenation

INTRODUCTION

A new Erbium:YAG laser employing micro-ablative technology provides a decrease in fine lines and wrinkles in the peri-orbital area in addition to a reduction in the appearance of acne scarring after one treatment. Skin appears brighter, fresher and more rejuvenated after just one treatment.

OBJECTIVE

The purpose of this study is to determine the safety ands efficacy of a low energy Erbium YAG laser based upon clinical and histologic analysis.

MATERIALS AND METHODS

Ten subjects (8 female and 2 male) age 18 or older (mean age 33) were randomized into two groups and were treated with the laser on the medium or high setting. Subjects were monitored immediately post-treatment, 5 days and 10 days after treatment. Improvement was measured by the participant, the principal investigator and a blinded investigator 10 days after the treatment session based on the following scale: no improvement, 0-25% improvement, 26-50% improvement, 51-75% improvement, and 76-100% improvement (see table below). Five participants elected to participate in the biopsy group, four subjects had a biopsy pre-treatment and immediately after treatment and one subject had a biopsy pretreatment, immediately after treatment and 5 days after treatment. Subjects were also asked to measure their brownness, redness, swelling, crusting and pain.

Improvements	Participant	Blinded Investigator	Principal Investigator
0%	10%	40%	0%
0-25%	40%	30%	60%
26-50%	10%	20%	10%
51-75%	20%	10%	0%
76-100%	20%	0%	30%

RESULTS

Subjects most commonly reported burning, erythema and mild edema in the treated area. The burning sensation ceased within a few hours after treatment. Mild edema and erythema subsided over the next 48 hours. Patients were instructed to use make-up for the erythema. Desquamation occurred up to 10 days with the majority of subjects achieving complete re-epithelialization within 7 days.

Subjects indicated that their skin felt “tighter”, “smoother”, and “brighter” after just one treatment. Biopsies taken pre-treatment, immediately post treatment with the device and five days post-treatment revealed that immediately post-treatment the cells of the spinous and granular layers in the epidermis were ablated. Five days post-treatment revealed an alteration in the elastic tissue and a thickening of collagen bundles in the papillary dermis consistent with early dermal remodeling were noted.

CONCLUSION

In conclusion, epidermal ablation and mild alteration of the dermal matrix consistent with early remodeling are noted after a single treatment with this novel low energy Er:YAG technology. This technology, as confirmed by the histology, is helpful for skin turnover as well as potentiating new collagen leading to plumper, smoother, and more uniform healthy skin. Dermal remodeling can lead to a decreased appearance of fine lines and wrinkles. (Figure 2) We would recommend this treatment as a “Friday peel” for patients as they can resume normal activities the same day however most subjects indicated they would feel most comfortable having a weekend rest period. Post-treatment patients are to avoid sun exposure and use a bland moisturizer and a sunscreen. Based upon this study protocol and the results, a series of 3 to 5 treatments every 1-2 months is recommended. This treatment series can be customized to suit the individual patient based upon the degree of photoaging. Because the device employs multiple energy levels, each treatment in the series can be tailored to the patient’s needs and desired outcome.

Subjects were asked to rate brownness, redness, swelling, blistering, crusting, and pain that they experienced over the day period of the study. Subjects rated this on a scale of 1 to 10 where 1=none and 10=terrible.

The table below represents the averages based upon the subject’s responses.

Brownness	Redness	Swelling	Blistering	Crusting	Pain
5.0	8.1	4.2	2.2	3.5	5.4

Figure 1.

A 2mm punch biopsy performed five days post-treatment on the high setting. Tissue was fixed in formalin and paraffin embedded prior to staining for elastic fibers. Black lines are decreased elastic fibers that are surrounded by collagen bundles. This is consistent with dermal remodeling.

Figure 2.

A) Pre-Treatment.

B) 10 days post-treatment on the high setting. The post-treatment photo shows a decrease in the appearance of fines lines and wrinkles in the peri-orbital area.

- Neil Sadick M.D., F.A.C.P., F.A.A.C.S Sadick Aesthetic Surgery and Dermatology Clinical professor of dermatology at Cornell University Medical College in New York City
October 17, 2005